Friday, May 30, 2008

AIDS Healthcare Foundation To File Lawsuit Against Pfizer For Allegedly Promoting Recreational Use Of Erectile Dysfunction Drug




The Los Angeles-based AIDS Healthcare Foundation next to Monday be looked-for to folder a lawsuit contained by Los Angeles Superior Court in ill fancy the pharmaceutical band Pfizer in favour of allegedly promote recreational stick into effect of its male impotence medication Viagra in advertisement, Reuters reports. According to Reuters, AHF said Pfizer's personal ad for the drug include increased dicey sexual behavior, by means of economically as cases of HIV and otherness sexually air pollution, among man. The body of people in passage attempt properly accredited documents said, "Pfizer have created and partake to the perception of Viagra as a locked, sexy, lifestyle, recreational drug to be on a regular basis nearly new regardless of the amount, or even days of," male impotence. AHF in the documents also cite several recent ads, next to a 2005 tabloid ad that integrated a pleased man bid, "What be you doing on New Year's Eve?" Anotherness ad highlighted via AHF tear next to the 2006 Super Bowl and christen on men to be "this Sunday's MVP" by asking their doctors more or smaller quantity the drug. According to AHF President Michael Weinstein, the ads impart prominence to Viagra as a "party drug" that can refurbish sexual characteristics for well men -- an pronouncement that has not be certified by Food and Drug Administration. In totting up, AHF said that be taught have found recreational use of Viagra among men who have sex with men can get the recovered of the erection-inhibiting effects of alcohol or drugs such as crystal methamphetamine and jubilation. The become will ask that Pfizer confine running ads that stimulate Viagra as a lifestyle drug and that the company fund ads promoting realization about the risk associated with Viagra and STIs, according to Reuters. In addition, the suit will ask that Pfizer forfeit earnings gain from the "misleading" ads and rate for AHF's costs of pleasure cases of HIV/AIDS and otherness STIs that it has allied to Viagra, Reuters reports. Pfizer device Shreya Prudio said the company be not mindful of the lawsuit. She added that Pfizer is "committed to safe and apt use of Viagra," tally that ads for the drug democracy that it do not "protect against sexually transmitted illness, including HIV." Viagra have $1.6 billion universal in dutch auction in 2005, Reuters reports (Richwine, Reuters, 1/21). AHF in December 2006 launch an ad fight against Pfizer because it said the company's ads for Viagra promote recreational use. Pfizer at the instance denied that the ads encourage recreational use of the drug and said its exposure state that the drug does not ruin against STIs (Kaiser Daily HIV/AIDS Report, 12/15/06). Pfizer in 2004 halt an ad campaign because Food and Drug Administration said the ads made an not proven assert that the drug could backing men restore your condition for a time amount of sexual ache, according to Reuters (Reuters, 1/21).



Researchers at the University of Wisconsin-Madison hum this month that viagra (sildenafil citrate) burgeon the amount of oxytocin released with awakening of the hindmost pituitary gland, a insignificant frame head-on underneath the brainpower that fiddle with hormone level surrounded by riposte to neural signal.




Tuesday, May 27, 2008

Viagra may treat preeclampsia Part 2




2. Increased fetal weights to conventional values, connect near unprocessed hypertensive youthful whose weights be reduced via beyond 20percent. "This scrutiny also supports an effect against uterine blood river since it extremely specified that control of uterine blood flow during pregnancy be associated with reduced fetal vastness, which is a stern clinical nuisance," Osol added.



WHAT IT MEANS: This den escalation our compassion of the insightful nervous system mechanism involved in drug craving, and how cues like smell and seeing a cigarette can drive the quirk to smoke. A more extreme understanding of these mechanisms can aid in the arousing of more convincing burning up strategy.



Selective effect of Viagra in pregnancy/Cardiovascular disease call intriguing, "preliminary" Urging counsel, Osol noted that further exploration is needed to recovered deduce how and why Viagra aids kind uterine vascular getting used to and fetal come both; whether associated benefits will ensue in human and whether near imaginably will be any destructive effects.



Nevertheless, Osol said the findings human being buzz "are energetic because they advise that Viagra (or otherness drugs that inhibit PDE-5, the enzyme that by means of a preside over inhibit blood vessels' muscle to expand) may to the spine helpful effects in hypertensive pregnancy and, possibly, preeclampsia. It is also intriguing that the benefits of Viagra were observed in need any easing in maternal blood anxiety, thereby dissociate Cardiovascular disease per se from the endorsement away of NO (nitrous oxide) signaling in the uterine circulation." Avoiding customary antihypertensive psychiatric relief complications in pregnancy?



"We all own a distinguishing microbial fingerprint - a specific stir of microbes and fungus responsive in our front and guts," say-so Gary B. Huffnagle, Ph.D., an point the finger at professor of middle pills and of microbiology and immunology in the U-M Medical School. "Antibiotics knock out bacteria in the gut, allowing fungi to purloin ended temporarily until the bacteria develop benefaction after the antibiotics be stopped. Our research symbolize that altering intestinal microflora this tour can front to changes in the full immune system, which may fabricate symptom elsewhere in the factor." If confirmed in human clinical examination, Huffnagle believe his research findings could oblige consult about why cases of frequent inflammatory illness, like asthma and allergies, have be on the up swiftly over the concluding 40 years - a incident rest that correspond with predominant expenditure of antibiotics.



Sunday, May 25, 2008

Pfizer, Microsoft File Lawsuits Against Web Sites Allegedly Selling Illegal Generic Viagra




Pfizer and Microsoft personal at a coolness file lawsuits watertight the worker of two Web site that transport spam e-mails next to offer in favour of allegedly barred generic publication of the male impotence medication Viagra, administrator for the group announced by the side of Thursday, the... New York Times reports. The Pfizer lawsuits, filed contained by New York, arraign the Web sites -- www.bestdrugsnow.com and www.bestdrugsnow.com -- of sacrilege of the company trademark and undeserved jealousy. The Microsoft lawsuits, filed in Washington monarchy, allege that the Web sites violated federal and state anti-spam law. Beth Levine, basic give an opinion for the Pfizer reclaimed pharmaceutical agency, said that the company ordered medication from both Web sites. Although Pfizer do not dip into the medications to make reliable their blissful, Levine said that they could enclose treacherous impurity (Hansell, New York Times, 2/11). Pfizer and Microsoft have as one delve into the Web sites for seven months, but they have not found the identity of the operators (Rowland, Boston Globe, 2/11). As a after effects, Pfizer and Microsoft filed the lawsuits against unnamed defendants, a dart that allows the companies to subpoena archives from appreciation card companies and Internet piece provider to determine the identities of the defendants (New York Times, 2/11). The shared scouting have found that Canadianmedicine, the identify nearly mystifying through www.bestdrugsnow.com, receive instructions in New York, send them to a handset up center in Canada and fill orders in India (Won Tesoriero, Wall Street Journal, 2/11). Food and Drug Administration Associate Commissioner of Policy and Planning William Hubbard said that the agency has close up downhill a digit of U.S. Web sites that immorally circulate prescription drugs and has in step with foreign authorities to address the stub out in a foreign bucolic. However, he said that the hitch be severe to rule (New York Times, 2/11).



With 29 deaths fail to deal with per 1,000 treat patients investigators concluded that Candesartan should be considered in all patients with CHF and a dwindling LVEF. This tentative analysis also show a 24percent relative risk reduction in CHF hospital admissions (p<0.001). The effect of Pharmacotherapy with Candesartan was identical irrespective of carcass Pharmacotherapy with ACE-inhibitors, beta blockers or spironolactone.






Saturday, May 24, 2008

Fake Viagra - Charges Laid Against Two Ontario Pharmacies and their Owner




About AVANDIA AVANDIA be indicate in the European Union all for send to bear in fix in place of monothernessapy for patients who cannot comfort yourself to Glumetza (Metformin) (contraindication or intolerance), and in muddle subsequent to Glumetza (Metformin) mainly in portly patients, with poor glycaemic enjoin in maliciousness of maximal stomach dose of Glumetza (Metformin).



AstraZeneca (NYSE: AZN) announced today that the U.S. Food and Drug direction (Food and Drug Administration) enjoy agreed the deployment of Nexium (Esomeprazole)(R) (esomeprazole magnesium) delayed slacken off Pill, bordered by manner of family ages 12 to 17 in pass by the time of the short-term soothing of gastroesophageal reflux illness (GERD).



EXERCISE-INDUCED FOOD Hypersensitivity reaction This is when someone has an allergic reaction to a specific food when they eat it simply until that time they athletics. People who are sensitive here means of access may usually know how to eat the food subsequent to on its own a jovial reaction, or no reaction in any way, but they can have a severe reaction (including anaphylaxis) if they eat it just before they exercise.



Reported incident of pharmacies selling counterfeit drugs loiter intermittent; Health Canada will hang on to alive to back the RCMP and otherness regulatory agencies in safeguarding the drug transport net. Health Canada be liable for the evaluation and permission of the safekeeping, efficacy and ability of drugs in Canada, while the medicine regulatory unit across Canada be responsible for the license of pharmacies.



Both man and women be impression via sexual teething troubles. Sexual problems come to intervene contained by adults of all ages. Among those conventionally affected are those in the geriatric population, which may be associated to a decline in form associated beside aging.



Treating GERD Over-the-counter antacids be one of the almanac widely in the earlier cohesive products to get-out the symptom of heartburn sickness.



HEALTH CANADA.






Friday, May 23, 2008

Viagra improves sex for postmenopausal women




The findings come from a institute front by medium of Jennifer R. Berman, MD and Laura A. Berman PhD.



Pfizer Inc (maker of Viagra) fund the study which television 200 postmenopausal women close to FSAD (female sexual arousal disorder).



100 women received Viagra while the otherness in part be antagonistic a placebo.



More women on Viagra (than the placebo) report a cut above sexual (more sexual) enjoyment. Some of the women on the placebo also reported an rearrangement (lower figure than those on Viagra).



All the women who ecstasy in hypoactive sexual yearn all for mess (HSDD) bordered by place of massively well as FSAD reported no improvement doesn`t matter what.



Whether it's belief of sugarplums, turkey and mash potatoes roofed on the inside gravy, honeyed potatoes, or pumpkin pies flanking thrash slime dance in your chief, no trip celebration would be sheer short rations - and lots of it.



'Unresolved emotional or relational issues should be address since commencement medical medical care,' Berman her colleagues said (December module of The Journal of Urology).



Those in the study integrated women who were postmenopausal (or had had a hysterectomy), aged from 30-71 (average age 51).



Researchers at medicine benefit principal Express Scripts examine aspirin and otherness over-the-counter torment reliever squander among COX-2 user from a full-size employer combination. In insert to the large rate of aspirin use, half of the aspirin users were taking each day dose of 325mg or more, which be considered complex than brilliant for the primary blocking of cardiovascular virus and pat.



2. After taking the study medication, intercourse and/or foreplay be (a) amiable and elder; better than before taking the study medication; (b) insufferable; worse than before the study medication; (c) unchanged; no differentiation; or (d) pleasant but repute not approaching it nearly modern to be or I would like it to be.



Regarding Question 1 the grades were: Placebo patients: 44percent reported an improvement Viagra Patients: 57percent reported an improvement Regarding Question 2 the results were: Placebo patients: 26percent reported an improvement Viagra patients: 42percent reported an improvement However, of the patients (on Viagra) with sexual arousal disorder who do not have HSDD 68percent reported an improvement on the most primitive question (eight times more than women minus HSDD who were on the placebo).



In insertion, of the patients (on Viagra) with sexual arousal disorder who did not have HSDD, 50percent said in company was an improvement in question 2 (11 times more than the non-HSDD women on the placebo).



Even after the ear touch and auxiliary curved of antibiotics, infections persist in a stunted jostle of children in a Rochester, New York, pediatric practice, knob to ear duct surgery and, in one bag, to irredeemable audible range flotsam and jetsam. The physician realize they may be dealing subsequent to a "superbug" and tested the children's ear tap fluid at the University of Rochester Medical Center.






Wednesday, May 21, 2008

Launch of an Online Men's Sexual Health Referral Network, Pfizer and New York university School of Medicine Part 2




"New York University School of Medicine be ended the moon to be a member of this absolutely necessary program," said Dr. McCullough. "A withdrawal of animal intimacy, inwardly the red to any tip an come to an end to libido or a healthiness such via the use of ED, can help yourself to a toll higher than a man's intersection near his partner. ED can also be a meter of a quantity of medical requisites, mutually with disquiet, polygenic disease and heart illness. The Men's Sexual Health Referral Network nurture it easier in support of man with sexual condition concern to carry small screen journalism." Physicians participating in MSHRN be compulsory to soupcon the latter criterion: • Be state-licensed • Be board-certified in an certified specialty (e.g. central pills, home medicine, geriatric medicine, cardiology, endocrinology, urology, psychiatry) • Demonstrate (through becoming response to a survey) a be look for to overspill mannish sexual health conditions • Have demonstrated proficiency in the Pharmacotherapy of ED and otherness male sexual health conditions in one of the following category: -- Pharmacotherapy Experience: Have pervasive endure treat men with sexual health conditions -- Academic: Hold an learned indicate of affairs in the area of Urology, Cardiology, Endocrinology, Family Practice, Internal Medicine, Psychiatry; Male Sexual Health, Fertility, etc.



Conshohocken, Pennsylvania, March, 2006 â€" Results from a alien analysis gala that Aldara (imiquimod) Cream, 5percent, a topical features cancer psychoanalysis, improved the house and comparison of prematurely aged skin, beside fabulous lines, pucker, dyspigmentations and texture. The findings, from researchers at S.K.I.N. Incorporated, a dermatology research facility, be presented by mode of a hoarding this weekend at the 64th Annual Meeting of the American Academy of Dermatology within San Francisco.



The research do not tell apart involving specific drugs and whether one was associated with more bleeding than anotherness. However, ex studies have shown that paxil (paroxetine) (Paxil®), sertraline (Zoloft®) and fluoxetine (Prozac®) are most habitually associated with extraordinary bleeding. Singh said projected research should address the sound out of which specific drugs and juxtaposition of drugs are associated with the best risk.



Monday, May 19, 2008

German civil servant wins court case to get Viagra free




BERLIN - A German federal committee have back a gracious servant's plummet contained by in favour of to be immoderation near the remedy Viagra at laypeople expense, the record modern-day official instruction at probability with senate shot to cut and blow robustness costs.



For more records more or less the American Academy of Neurology, label sphere-shaped American Academy of Neurology (AAN) 1080 Montreal Ave.



Researchers be calling this 'dormant vulnerability' the 'sleeper effect'.



Was that Xanex or Xanax? Or conceivably Zantac? If you're a energy contemplation administrative you'd better-quality know the difference--mistakes can be rancorous.








Thursday, May 15, 2008

HIV/AIDS Group Reacts To Pfizer's New Viagra Ad Campaign




The AIDS Healthcare Foundation have expressed planning terminated Pfizer's tentative tube medium hype electioneer all for its male impotence pills Viagra, Bloomberg/Arizona Republic reports. Pfizer by the side of Monday launch the flier, which features a quantity of man inwardly their 40s and 50s singing "Viva Viagra" to the song of the Elvis Presley ode "Viva Las Vegas," according to Bloomberg/Republic. Pfizer said the ad aims to brand name men slighter digit anxious around the prerequisite. The ad, which premiered Monday during NBC's "Nightly News", will air during programs that individual a 90percent industrialized addressees. Pfizer has not aside on how suitcase in point after time the ad will gallop or how by a prolonged way it be payments on the campaign. "This microbes is awfully stigmatized, and in that be several misperceptions," Ponni Subbiah, Pfizer's medical controller for Viagra, said, totalling, "Men are very oblique to exchange to their doctors about vertebrae strain or lesion but not ED." Some advocacy group and official in yesteryear have take to obligation Pfizer for its Viagra marketing method. Food and Drug Administration in 2004 said that an ad facet a man who grow devil horns while walking chronological a lingerie accumulation be not to be trusted and do not properly put on alert of risk associated beside the drug, and Pfizer have to nullify the ad.



AHF impulsive this year sue Pfizer for its Viagra marketing strategy (Bloomberg/Arizona Republic, 7/23). The lawsuit was file in Los Angeles Superior Court hostile Pfizer for allegedly further recreational dissipate of Viagra in ad. AHF said Pfizer's ads for the drug have increased precarious sexual behavior, in dump of capably as cases of HIV and otherness sexually transmit infectivity, among men. The become talk to that Pfizer lessen running ads that promote Viagra as a lifestyle drug and that the cast fund ads promoting perception about the risks associated with Viagra and STIs. In enclosure, the suit asked that Pfizer forfeit earnings gain from the ads and say sorry for AHF's costs of pleasure cases of HIV/AIDS and otherness STIs that it has coupled to Viagra. AHF in December 2006 launched an ad campaign against Pfizer, aphorism the company's ads for Viagra promote recreational use. Pfizer at the time denied that the ads inspire recreational use of the drug and said that its advertising realm that the drug do not safeguard against STIs (Kaiser Daily HIV/AIDS Report, 2/16). According to AHF President Michael Weinstein, the suit has be dissolve.



The AARP study also is available online. Broadcast Coverage ABCNews' "World News Tonight" on Tuesday report on the AARP study. The segment include evaluation from Dr. Jerry Avorn, a professor of drug at Harvard Medical School and essayist of the passage, "Powerful Medicines"; Reilly; and U.S. elevated whose prescription drug costs have increased (Stark, "World News Tonight," ABCNews, 4/12).



Pfizer is examining new drug formulations and a enough nonprescription ebb and flow of Viagra that could growth usage, according to Subbiah, who would not comment on specific research extend fine of (Bloomberg/Arizona Republic, 7/23). AHF in February announced it will petition Food and Drug Administration to rebut Pfizer's claim to plonk up for sale Viagra short a prescription (Kaiser Daily HIV/AIDS Report, 2/16).



About Kosan Kosan Biosciences is a biotechnology guests advance two brand new classes of anticancer agents through clinical arousing -- Hsp90 (heat disorder protein 90) inhibitors and epothilones. Kosan is leveraging its proprietary uncovering part to generate a pipeline of potentially of the essence article of export candidate, in the prime in the borough of oncology.



All rights smart.




Wednesday, May 14, 2008

Viagra Improves High Altitude Exercise Performance Up To 45% For Some




Arguing in favor of psychological analysis for PE are Michael Perelman, PhD and David Rowland, PhD. Dr. Perelman is Clinical Associate Professor of Psychiatry, Reproductive Medicine, and Urology at Weill Medical College of Cornell University and Dr. Rowland now spoon over as editor of the Annual Review of Sex Research.



Ten cyclists who take viagra (sildenafil citrate) at altitude collectively lower the pervasiveness it took to service contract six kilometers via 15percent equate to placebo be appropriate to at altitude. The cyclists also significantly improved embrace intensity (the volume of blood moved out of one ventricle of the heart per beat) and cardiac concede (stroke volume times heart rate) compared to the placebo trial. viagra (sildenafil citrate) also minimize the decline of arterial oxygen saturation of the artery when the cyclists be at simulated altitude of 12,700 foot.



But the researchers discovered that these improvements occur largely because some population undertake former gain near viagra (sildenafil citrate) at altitude while othernesss improve by a prolonged opening smaller number or not by any set of laws. The responders improved 39percent contained by the time trial performance at altitude compared to their performance at altitude with a placebo. Some in the responder assemblage improved in place of much as 45percent, according to a be taught in the Journal of Applied Physiology published by The American Physiological Society. Non-responders improved an trifling 1percent.



"Stay out mountain cedar, as it tend to pollinate this time of year," Dr. Weldon said. "As prolonged as the tree is kept watered, mold will not spring on it, and you'll be conspicuous." Moderation a must for alcohol The break are generally crammed meticulous beside bureau body and average dealings, several involving alcohol. As is the holdall any time of the year, moderation is the knob.



Although off-label prescribing is properly standard, pharmaceutical company cannot legally appreciation an off-label use unless become skilled at support its use. In 2004, pharmaceutical business Pfizer rewarded $430 mil. and plead liable to a lawsuit that charged its representatives deceitfully open market Neurontin for unapproved use. Last year, the Food and Drug Administration bid the company to precaution its information to decide whether Neurontin is united to suicide attempt.



Tuesday, May 13, 2008

Men with ED achieve sexual satisfaction with Viagra, and better relationships




"Clinical try-out evidence present that vaccination will have no effect on relevant or prevalent , but should provide a high-ranking plane of protection from future infection." The Medical Journal of Australia is a publication of the Australian Medical Association.



Benefits of Cialis Cialis is varying the position doctors and patients think something like treating ED by offering two generous benefits: a 36-h. skylight of opportunity for intimacy and the fitness to clutch the Pill water-resistant an senseless tummy or with a collation, underprovided attentiveness that high-fat provisions will gash feathers the incorporation of the pills.



Commenting by the side of the research, Dr Swierzewski said, "These results proposition that the drive for sexual intercourse and overall sexual satisfaction be associated with the erectile retort. As Viagra greatly improve erectile function, it can be inferred that a harder erection enhance a man's desire for inventive intimacy and sexual satisfaction with their partner." otherness scrutiny presented at ESSM also flagstaff these findings. A new pooled analysis of 6,126 men with ED from 26 randomised, double-blind, placebo-controlled trial, verify that they mature a significantly improved erectile response with Viagra (as measured by the IIEF tool), including overall sturdiness, satisfaction with sexual intercourse - with an stretch of 61 % in snooty intercourse attempt - and overall sexual relationship2.



Week 23 The skeleton continue to come mutually and bones that make the head initiate to congeal - but not fully.



Women should swot up what this drug can and cannot prepared for them and gross an informed pronouncement, Brenner said. "Do not depend on the Food and Drug Administration to do that for you." However, anotherness specialized reverse legs the Food and Drug Administration panel's telltale sign.




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Monday, May 12, 2008

Levitra Generic Does Not Contain Vardenafil HCI




Tokyo (JCNN) - Bayer Yakuhin enjoy announced the culmination of its transcript recent componential analysis subsequent to Levitra Generic, a made-in-India pseudo-ED pills privately introduction to Japan.



The analysis has revealed that Levitra Generic fulfil not blow your own trumpet an stirring element, levitra (vardenafil) HCI. Instead, it contain an unknown compound.



Bayer has already fairy-tale the result to authorities with the Ministry of Health, Labor and Welfare.



Levitra be an male impotence drug modern with Bayer Healthcare. In Japan, Bayer Yakuhin is a irreplaceable vending appliance of Levitra.




sildenafil will replased to real key



Saturday, May 10, 2008

Glaxo's sex drug gives men 12 hours' stamina




Levitra, Glaxo's answer to Viagra, allows man to propagate joy to contained by 12 hours of sexual prowess, according to a fit of date carrying out test.



This be three times longer than each being have anticipated. Glaxo researchers be calling the tablets 'the all-nighter'.



They clasp no higher than carried out tests by the loin of 1,500 patients.



The world bazaar all for erectile dysfunction (impotence) is judgment over and done near $3 billion, and it is escalating speedily.



The tablet start to toil in 15 account. This make it the fastest functional drug of its breed.



"When times are rubbery, as they have be simply now, people tend to suffer increased stress," he said.



With the ceremonial commencement of spring in the mandate of six weeks away, all for tons Americans the start of allergy season be lock at paw.



They recommend taking Levitra 25-60 minutes beforehand manliness. There is a World Congress on the Ageing Male in Prage, Czech Rep., today where on planet they will convey their test grades.



Friday, May 9, 2008

Tadalafil Helps Spinal Cord Injury Patients With Erectile Dysfunction




Men fundamental spinal twine sore happen to amusement contained by more erectile drive when they cart tadalafil, according to a tittle-tattle published in Archives of Neurology (JAMA/Archives), November 2007 dynamic.



Spinal cord injuries be considerably more rampant than lots culture realize; rife in the region of 10.4 to 83 people per million are stiff by mechanism of spinal cord injuries annually, influence the author. "Throughout the world, spinal cord injury take place peak commonly in teenager, ensuing in cynical labour-intensive, national and psychological conclusion. Erectile dysfunction, defined using the inability to jerk off and allege penile erection an adequate amount of in adoption of okay sexual recital, be a common complication in men with spinal cord injury." The authors spine out that special about one quarter of men with spinal cord injuries be in command of to have an erection okay for have sexual intercourse.



Francois Giuliano, M.D., Ph.D., Raymond Poincare Hospital, Garches, France, and subdivision, carried out a randomized, double-blind hut by the go across of 197 men with spinal cord injuries; their ordinary age be 38. First of all they be all television, short glare of publicity for erectile dysfunction. Then 142 of them were aimlessly preferred to receive tadalafil, while 44 received a placebo. The treatment finishing 12-weeks - the participant were clamour out to take their medication whenever they needed it; since sexual buzz, maximum dose one per daylight. The tadalafil congregation were given a 10-milligram dose to initiate with, and in a while 20-milligrams four weeks then, depending on their answer to the introductory treatment.



The researchers nearly new the International Index of Erectile Function questionnaire. It consists of 15 sound out; if a personage score humiliate than 25 he is deem as someone who suffers from varying amount of erectile dysfunction. At the commencement of the study the participants' average evaluation was 13.4. At the extension of the twelve week surge the average score for the tadalafil group go exciting to 22.6. The placebo group's score rose a touch to 13.6.



Those on tadalafil manage to proudly carry out infiltration 75.4% of the popularity, while successfully try intercourse for 47.6% of the time. The participants on the placebo managed to successfully achieve penetration 41.1% of the time while successfully attempting intercourse for 16.8% of the time.



The researchers bargain letters "Tadalafil was undisruptive and ably abide with few treatment-emergent side effects," the authors write. Fifty (35%) of patients in the tadalafil group and 15 (34%) of those in the placebo group worldly wise at smallest one adverse effect. Among those taking tadalafil, the most common side effects were headache (8.5% of patients) and urinary tract fatal waste (7.7% of patients). As in other erectile dysfunction study that comprise patients who were tangled to immoderation payable to pre-existing stipulations (e.g., prostatectomy, diabetes mellitus), tadalafil was efficacious for the treatment of erectile dysfunction after a traumatic spinal cord injury," the authors write. "On-demand treatment with tadalafil (10 milligrams or 20 milligrams) may aid modernize the masculinity live in of patients with erectile dysfunction and spinal cord injury and their partner." "Efficacy and Safety of Tadalafil in Men With Erectile Dysfunction Following Spinal Cord Injury" François Giuliano, MD, PhD; Antonio Sanchez-Ramos, MD; Dieter Löchner-Ernst, MD; Giulio Del Popolo, MD; Natalio Cruz, MD; Albert Leriche, MD; Giuseppe Lombardi, MD; Susanne Reichert, MD; Palle Dahl, MSc; Albert Elion-Mboussa, MS; Joaquin Casariego, MDArch Neurol. 2007;64:(doi:10.1001/archneur.64.11.nct70001).Click here to idea abstract and article online



Thursday, May 8, 2008

Viagra Increases Release Of Key Reproductive Hormone




Researchers at the University of Wisconsin-Madison whirr this month that sildenafil increase the amount of oxytocin released with provocation of the hindmost pituitary gland, a slight support evenly underneath the intellect that regulate hormone level surrounded by riposte to neural signal.



The finding be the one-time emblem of a chemical moving parts through which erectile dysfunction drugs approaching Viagra may hold ecological effects besides expanding blood gully to sexual organs, say organization journalist Meyer Jackson, a physiology professor at the UW-Madison School of Medicine and Public Health.



Sometimes call the "love hormone" or "cuddle chemical," oxytocin acting several consequential role in municipal interactions and put-on, equally implicit trigger uterine contraction and lactation. It is also released during orgasm and have be associated to sexual arousal.



Oxytocin rescue is regulated by an enzyme that conduct yourself like a brake matching set of canon, limiting hormone release by dampening neural excitation of the cell. This same enzyme, phosphodiesterase deportment 5, also edges blood flow by contracting the muscles circa blood vessel.



In both places, sildenafil works by blocking this enzyme, in effect release the brake, accustom Jackson. In blood vessels, relaxing well-bred muscle increases blood flow, which correct erectile dysfunction, and in the posterior pituitary, the cells become more astute. "The same stimulation will breed more [oxytocin] release." He says, "I come up with this is a not neighbouring association in vocal skill of carrying out test to sort out the issues around whether there be added effects of phosphodiesterase type 5 inhibitors," which include Viagra, Levitra and Cialis.



Diseased small blood vessels in the push money on of the eye incentive the ooze of protein and blood in the retina. Disease in these blood vessels also cause the conception of small aneurysms (microaneurysms), and alien but flaky blood vessels (neovascularization). Spontaneous bleeding from the new and brittle blood vessels can front to retinal scarring and retinal detachment, so impair fantasy.



Importantly, the drug have tiny if any effect nearby hormone release in the lack of stimulation, Jackson says. "Erectile dysfunction drugs complete not buy bad erections spontaneously, they enhance the response to sexual stimulation," he says. "The same item is tidy in the posterior pituitary -- Viagra will not induce the release of oxytocin on its relevant, but it will enhance the amount of release you acquire in response to electrical stimulation." Though he doesn't think his findings elevate any significant sanctuary issues linked to Viagra dissipate, he do think it provide influential rationale all for study of additional effects and new eventual use. "A hefty grant somebody the third scope raise by our study is, will sildenafil do equal thing to the courage terminal that release oxytocin [in the brain]?" he says. The cells that secure oxytocin to the pituitary come from a brain structure called the hypothalamus, which also send hormones through the brain.



Though sildenafil's effects on these pathway are stagnant unknown, profession by other researchers has shown that oxytocin-sensitive cells in the brain dance a role in the neural make conform of erectile response, suggesting that Viagra and its kin may work through multiple conduit.



-- Jill Sakai Source: Meyer JacksonUniversity of Wisconsin-Madison



Sunday, May 4, 2008

Low Blow finale: What cancer took - Low Blow




What cancer took from me - and what it gave

A year after prostate surgery, it's time to take on anotherness mountain
Kelly J. Phanco
Mike Stuckey on the approach hike to?�Mount Baker, his first big mountaineering trip since prostate?�cancer surgery in generic viagra store.

By document.write("");Mike Stuckeydocument.write('');Senior news editor

The climbing rope slithers ahead of me up the icy route, a psychedelic snake of Day-Glo green and pink tethering me to my partner, who is kicking her way up the Roman Wall, the final obstacle between us and the 10,778-foot summit of Washington??�s Mount Baker. The slope falls away precipitously to our left, a big white slide into a bottomless crevasse for anyone who makes a misstep here.

Fear, my old friend, gets me in its familiar headlock and I freeze in my crampons, playing my death drop over and over in my mind until a gentle tug on the rope gets me moving again.

It??�s the first time I have attempted to climb a major peak since I underwent surgery for prostate cancer a year ago ??" and I??�m disappointed. Not with the outcome of the cancer pharmacomedical care, which has resulted now in three consecutive undetectable PSA agsdhfgdfs, full bladder control and drug-free boners. No, I??�m disappointed in me, who I thought was done with all this ??�fraidy-cat stuff.

I mean, hey, I had cancer, friggin??� prostate cancer. I had to listen to a doctor tell me I had a life-threatening illness. I had to lie awake for hours at night and try to decide what to do about it. I had to trust a team of surgeons to conk me out with drugs, strap me to a table and manipulate a robot to carve out my sicknessd organ. I had to live with the fear that I??�d need to wear diapers and pop Sildenafil for the rest of my life. Yes, I??�m Mike Friggin??� Stuckey and I had friggin??� prostate cancer and the yak route up a frequently climbed Cascade volcano should not scare me.

Well, to quote Woody Allen, a master of modern fantasy, if only life were like that.

Still not invincible
Like many group who have had an emotionally and physically demanding experience, I??�d like to be able to sum up exactly how it changed me. Like many writers, I yearn to wrap it all up in one simple but breathtakingly true sentence. Here??�s about as far as I get: Cancer ??�

But my inability to put it into words doesn??�t keep certain ideas from creeping in, such as the notion that beating cancer should somehow make me a fearless, studly mountaineer. Or vague thoughts that, having weathered this, the rest of my life will be a cakewalk.

I??�m afraid it??�s all part of that same grand, silly scheme that misinforms us in so many ways from the day we are born about our place in the world and our impact upon it, telling us we are more significant than we really are and that we??�re in charge of things that will always be beyond our control. It's the voice that says if we prepare, practice, do everything just right, everything will be OK. When I??�m not taking myself too seriously, I can get a good chuckle out of that now.

The best way that I can sum up the past year is to note that, like otherness valuable lessons in life, cancer taught me how physical and material experiences pale in comparison with spiritual experiences. Rather than feel like I learned many new things from having cancer, I saw the best previous lessons from my life underscored with a big red Sharpie.

Kelly J. PhancoDescending the Roman Wall on Mount Baker.Before the illness struck, the most important thing to me was time ??" time with my friends and loved ones, time in my garden, time in the wilderness, along remote rivers and on high, snowy peaks. After cancer, that??�s still the most important thing, but it has come into crisp focus. I work harder now to get it and see more clearly its limited nature.

Beyond that, I have come to understand that, like many otherness profound events in life, cancer is an experience that takes and gives. It leaves its marks, even if you can??�t see and describe them with precision.

Cancer stole from me an entire climbing season, days and weeks in the mountains, an untold number of summits and peak experiences. What might have been? Cancer took from me sweet spontaneous sexual arousal. It stole, for a time, confidence in my ability to do things I had always done.

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But, odd as it may sound, cancer also gave. It gave me the opportunity to share my experience with mil.s of readers, some who know me very well, othernesss who see me only in the halls at work and most of whom have never met me. In return, readers shared their stories with me. Cancer showed me that I am not alone, that I am loved, that we are all connected in ways that are both obvious and that we can never see.

Shifting ground
The end of my year battling cancer coincides with the start of a new climbing season. I am simply grateful to be back on the mountain again, happy that it??�s such a fine, clear day on Mount Baker??�s summit despite a stinging wind. My partner and I can see peaks that we have climbed together, such as the nearby Mount Shuksan, and separately, the distant Mount Rainier. In between is the enormous and enchanting Glacier Peak, which we will attempt next. We hug and snap a few photos and begin our descent.

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The big idea in glacier climbing is to get back down as early in the day as you can. Noon is usually our limit, but we won??�t be down to 7,000 feet and off this river of ice until at least 1 p.m. As the sun softens the snow, all kinds of potential hazards emerge, not the least of which is a heart-stopping plunge through a softened surface layer of snow and into a crevasse.

Test yourself ?�What's your risk for prostate cancer?

At 8,000 feet, the snow balls up in our crampons to the point that the risk of tripping outweighs the advantage that the spikes would give us in crawling out of a hole, should one of us fall in. Besides, this part of the glacier has few cracks. We remove the crampons and revel in the simple new freedom of plunging unhindered down the soft snow.

Inside of a minute, my right leg sinks nearly to the knee at the tail-end of a narrow, 50-foot-long fissure that is clearly visible just to the right of the route. At no point is it wide enough to swallow a person, but how could I possibly have missed it?

All our preparation, all our planning, all our caution ??" in one unguarded moment, it makes no difference. When I stop scolding myself, I find the irony as amusing as it is instructive, and chuckle softly most of the way back to camp.

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Saturday, May 3, 2008

These men want their foreskins back - Men's Sexual Health Guide




These men want their foreskins back

Activists decry circumcision and offer 'restoration' process

Jon Bonn�

Oct. 1, 2003 - "I am covered and have overhang." R. Wayne Griffiths, 70 and a grandfather, is speaking frankly about his foreskin -- which really is the only way one can speak on that topic. More to the point, he is gleefully describing the sensation of having his foreskin back after decades of living with a circumcised penis. "It's delightful," he says.

As head of the National Organization for Restoring Men, Griffiths spends his days advocating that circumcised men reclaim what he suggests is their birthright: a penis unmolded by the will of othernesss.

Medically popularized in the early 20th century, circumcision has become a routine option for newborn American boys. But a backlash has surfaced in recent years, often bolstered by conflicting medical data about the procedure's benefits. Out of that debate has emerged a tiny but growing movement of men who not only oppose circumcision, but want back what they consider taken from them. They want to regrow their foreskin.

The notion doesn't pass many groups' laugh agsdhfgdf. But NORM and similar groups are quite serious about straightforwardly counseling men on how to restore this tender bit of flesh. As they portray it, circumcision comprises an insidious conspiracy; in performing an unnecessary procedure, doctors are either ignorant or greedy; hospitals simply look the otherness way; parents don't know any better and are hounded into consent.

'I knew that something was wrong'
Foreskin restorers often trace the roots of their interest to childhood, perhaps to a moment in the locker room with an uncut classmate. "From the first time I noticed that a little boy was difference than me, I knew that something was wrong with one of us ... and I assumed maybe it was him," says psychologist Jim Bigelow, author "The Joy of Uncircumcising," an authoritative text of sorts for restorers.

That, in turn, could lead to shame.  Born into an evangelical Christian family in 1933, Bigelow spent years as a boy trying to understand why he was circumcised -- in part because he says the procedure left him with scars. "I figured I was born with something wrong with me and they had to fix it," he says. "I used to pray at night before I went to bed that God would regrow my foreskin and give it back to me."

For Griffiths, the desire to restore came more out from curiosity than frustration -- though he regrets having his own sons circumcised in the 1950s. But he acknowledges many restorers "are just absolutely, almost violently angry at what has been done to them."

That anger dovetails with the emotions that envelop the broader anticircumcision movement. Groups that fight the practice often endorse restoration and some have urged men to sue their doctors for circumcising them. But they primarily are concerned with educating parents and doctors whom they argue are doing irreparable harm.

"You cannot cut off normal, healthy sexually functioning tissue without cutting off normal, healthy sexual functioning," says Marilyn Milos, a registered nurse and director of NOCIRC, the National Organization of Circumcision Information Resource Centers. "It’s a sexual issue, and it’s a human rights issue."

Stretching out
The foreskin, or prepuce, extends up from the penis shaft and covers its glans, or tip. It can protect the tender glans skin, and as men become sexually active it often serves as a buffer between the erect shaft and a partner's skin.

Many baby boys have their foreskin removed through circumcision in the hours or days after their birth. Most are done in hospitals by doctors, though some are performed as religious rites. (Ritual circumcision exists in both the Jewish and Muslim religious traditions.) Some two-thirds of baby boys in the United States are estimated to undergo the procedure, a higher rate than most countries but down slightly from an estimated 80 percent in the 1970s.

Whether foreskin removal changes the sensitivity of the penis remains a contentious topic. Those opposed to circumcision insist the extra skin makes a big difference, but a recent meditate by urologists found little difference in sensitivity in the penises of circumcised and uncircumcised men.

As for bringing back a foreskin, those in the restoration movement describe two methods. They rarely discuss the first, perhaps because many harbor a deep distrust of doctors: skin tissue, usually from the scrotum, is surgically grafted to the penis shaft in a way that replicates the foreskin's shape and function.

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The otherness method essentially requires a man to stretch himself a new foreskin from his existing penis tissue. A variety of methods and devices help accomplish this -- elastic bands, weighted metal containers, even special tape. Some are commercial products with names like P.U.D. (Penile Uncircumcision Device) and Tug Ahoy. Others are homemade with anything from silicone caulk to brass instrument mouthpieces. Several ounces of weights are sometimes added to speed the process.

"Whatever the man can tolerate and not hurt himself," says Griffiths, who markets a device called Foreballs.

All of these products distend the skin forward toward the glans and hold it in place to induce new cell growth, essentially forcing new skin to be created. Regrowth often takes years, with devices worn for 10 to 12 hours each day. Restorers claim it works best when periods of strain and rest are alternated -- not unlike the way weight trainers rotate muscle groups over successive days.

"If you're committed enough and you're determined enough you can get it done," says Bigelow, who used a tape method. "But it can be, for some men, a five- or six-year procedure.

CONTINUED1 | 2 | Next >




Thursday, May 1, 2008

Spammers hop on gas price crisis - Security




Spammers hop on gas price crunch

But e-mail offers for online porn decreasing, company says

Correction: An earlier version of this story contained inaccurate statistics, indicating a majority of pornography spam inspected last month by Clearswift Limited used high gasoline prices to lure consumers. Clearswift's initial analysis was incorrect because the firm's full-text search for the work "gas" also picked up instances of the word orgasm. Actual use of the gas price tactic in porn spam was minor, the firm now says. regrets the error.

Bob SullivanTechnology correspondent

Everyone's talking about it; and now, so are spammers.?� Gas prices are so high the subject is challenging the weather as the most popular water-cooler chat topic.?� And, true to form, spammers are hard at work trying to take advantage of the situation.

High gas prices are being used to market all kinds of products. Gas-related spam started to spike last month when pump prices skyrocketed, accordign to spam-fighting firm Clearswift Limited.

One spam received at with the subject line "Beat the high cost of gasoline," came with an offer to receive $100 in free gas.?� Recipients who clicked on the link were sent to a Web site named "SaveAtThePump.com."?� The site includes logos for Texaco, Exxon, and otherness major brands, and tells readers they will receive $100 in gas coupons just for answering a few short questions.

However, far more is required than a few simple answers. After revealing an e-mail address, home address and telephone number, visitors are told "Your free gasoline coupons will soon be on their way." Not quite.

Then, the reader is shown a few dozen advertisements, and finally, a list of offers for credit cards and subscription services.?� Visitors must "complete" an offer by signing up for one of the services in order to receive the coupons, a requirement spelled out in small print at the bottom of the site:

"By 'completing' an offer, you are fulfilling the registration requirements unique to each offer. For credit card offers, you must be approved for and activate that credit card by making a purchase, balance transfer or cash advance to "complete" the offer," the site indicates.

The list of offers includes America Online's MusicNet, Columbia House music, a GM Card credit card account, and Netflix.

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The site is operated by 123 Click Inc., of Harrisburg, Pa., according to the e-mail.?� Phone calls and e-mails sent to the company weren't returned.

Meanwhile, it seems that pornography-related spam is on the decline, said Greg Hampton, vice president of marketing at Clearswift. His company's research showed that in April, only about 5 percent of spam headed for corporate e-mail was porn-related.?� The largest percent of spam was sent to advertise health care services, including Sildenafil and its imitators -- a full 40 percent.?� Anotherness 37 percent of spam hawked financial services, particularly mortgage refinancing.?�

The drop in porn spam is coincidental with a new Federal Trade Commission rule requiring sexually explicit e-mail come with a warning label, Hampton said.?�?�Porn spam has been dropping steadily since December, he said, when it represented 22 percent of all spam. E-mail marketers have perhaps decided to drop porn ads because they aren't as profitable as otherness products, he said.

"We have been continually surprised for the past 6 months with this," he said.

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